On further investigation, I guess adobesystems.com is a valid "permission email marketing" site. There is probably no need to filter the adobesystems.com site itself, BUT searching for "adobesystems.com !safeoff" returns many linkfarm pages that you may want to consider filtering:
havesexatwork dot org
keithosullivan dot com (flagged as malware site by Google Safe Browsing)
mediawebsolutions dot it /images/portfolio/TN/thumbs/page1266.html
mpg-faq dot com
build1userver dot com
funny-youtube dot videosphotosmovies dot com
top100today dot com
and a bunch of adult sites.
Moderator's Note: Removed direct link to spam website. (We don't want them to get any SEO juice from Duck.co!)